Poster Session 1: Immune Reconstitution

Track: Contributed Abstracts
Wednesday, February 13, 2013: 6:45 PM-7:45 PM
Hall 1 (Salt Palace Convention Center)
173
Lower Lymphocyte Count At Day 30 Predicts Worse Overall Survival with Tacrolimus and Mycophenophelate Mofetil Use for Gvhd Prophylaxis: A Large Retrospective Analysis
Zaid Al-Kadhimi, MD, Karmanos Cancer Center/ Wayne State University; Zartash Gul, MD, University of Kentucky/Markey Cancer Center; Emily Van Meter, PhD, University of Kentucky; Muneer H. Abidi, MD, Wayne State University/Karmanos Cancer Center; Abhinav Deol, MD, Wayne State University/Karmanos Cancer Institute; Lois Jeanne Ayash, MD, Karmanos Cancer Institute; Lawrence Lum, MD, DSc, Karmanos Cancer Institute; Voravit Ratanatharathorn, MD, Karmanos Cancer Institute; Joseph Uberti, MD, Karmanos Cancer Institute - Wayne State Univ

174
Lymphocyte Count Above 300 X 106/Ml 90 Days Post Transplant Predicts Better Overall Survival After Alemtuzumab for Unrelated Donor Stem Cell Transplant
Zartash Gul, MD, University of Kentucky/Markey Cancer Center; Samuel D Bailey, M.D, University of Kentucky; Emily Van Meter, PhD, University of Kentucky; Zaid Al-Kadhimi, MD, Karmanos Cancer Center/ Wayne State University; Amber Lawson, University of Kentucky; John Hayslip, M.D., University of Kentucky; Gregory P Monahan, M.D, University of Kentucky; Brent Shelton, PhD, University of Kentucky; Kevin T McDonagh, M.D, University of Kentucky; Dianna Howard, MD, University of Kentucky Chandler Medical Center

175
Immune Reconstitution Following Reduced Intensity Stem Cell Transplantation for Non-Malignant Disorders in Children
Jeffrey J Bednarski II, MD, PhD, Washington University School of Medicine; Catherine Le, Washington University School of Medicine; Lisa Murray, MA Biology, Washington University; Robert Hayashi, MD, St. Louis Children's Hospital; Lolie Yu, MD, Children's Hospital/LSUHSC New Orleans; Jignesh Dalal, Children's Mercy Hospital; Naynesh Kamani, MD, Children's National Medical Center; David A. Jacobsohn, MD, Children's National Medical Center; Michael A. Pulsipher, MD, Primary Children's Medical Center/Huntsman Cancer Institute, University of Utah School of Medicine; Aleksandra Petrovic, MD, All Children's Hospital; Ka Wah Chan, MD, Texas Transplant Institute; Michael Grimley, MD, Texas Transplant Institute; Paul Haut, MD, Riley Hospital for Children/Indiana University; Roberta Adams, MD, Mayo Hospital; Dorothea Douglas, MD, Phoenix Childrens Hospital; Sonali Chaudhury, MD, Hematology/Oncology/Stem Cell Transplantation; Andrew Gilman, MD, Levine's Children Hospital; Jennifer Jaroscak, MD, UNC-CHapel Hill; Martin Andreansky, MD, PhD, University of Miami Miller School of Medicine; Kirk R. Schultz, MD, BC Children's Hospital/UBC; Jennifer R Willert, MD, Children's Hosp San Diego; Shalini Shenoy, MD, Washington University in St. Louis

176
Early Lymphocyte Recovery Predicts Superior Overall Survival After Unmanipulated Haploidentical Blood and Marrow Transplantation for MDS and Acute Myeloid Leukemia Evolving From MDS
Ying-Jun Chang, MD, PhD, Peking University People's Hospital; Xiang-yu Zhao, MD, PhD, Peking University People's Hospital; Lan-ping Xu, MD, Peking University People's Hospital; Dai-hong Liu, MD, Peking University People's Hospital; Kai-yan Liu, MD, Peking University People's Hospital; Yu-hong Chen, MD, Peking University People's Hospital; Xiao-Su Zhao, MD, PhD, Peking University People's Hospital; Wei Han, MD, Peking University People's Hospital; Huan Chen, MD, Peking University People's Hospital; Feng-rong Wang, MD, Peking University People's Hospital; Meng Lv, MD, Peking University People's Hospital; Xiao-jun Huang, MD, Peking University People's Hospital

177
Evolution and Clinical Implications of the T Cell Repertoire Following Cord Blood Transplant
Colleen Delaney, MD, MSc, Fred Hutchinson Cancer Research Center; Ryan Emerson, PhD, Adaptive Biotechnologies; Filippo Milano, MD, PhD, Fred Hutchinson Cancer Research Center; Anna Sherwood, PhD, Adaptive Biotechnologies; Adrienne Papermaster, Fred Hutchinson Cancer Research Center; Katherine A. Guthrie, PhD, Fred Hutchinson Cancer Research Center; Christopher Carlson, PhD, Fred Hutchinson Cancer Research Center; Edus H. Warren, MD, PhD, Fred Hutchinson Cancer Research Center; Harlan Robins, PhD, Fred Hutchinson Cancer Research Center

178
Impact of Atorvastatin On Cellular Immunome of Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (AHSCT)
Yvonne Efebera, MD, The Ohio State University; Susan Geyer, Ph.D., The Ohio State University; Anissa Bingman, MS, The Ohio State University; Rhonda Kitzler, B.S, The Ohio State University; Patrick Elder, MS, Arthur G. James Cancer Institute; Carrie Hennelly, B.S, The Ohio State University; Leslie A Andritsos, MD, The Ohio State University; Samantha Jaglowski, MD, Ohio State University Medical Center; William Blum, MD, The Ohio State University; Rebecca Klisovic, MD, The Ohio State University; Sam Penza, MD, The Ohio State University; Sumithira Vasu, MBBS, Ohio State University Medical Center; Craig C Hofmeister, MD, The Ohio State University; Don M Benson, MD, PhD, The Ohio State University; Steven M Devine, MD, The Ohio State University; Gerard Lozanski, M.D, The Ohio State University

179
Different Natural Killer (NK) Cell Subsets Elicit Unique Target Induced Immune Responses: Implications for Assessment of Posttransplant Functional Recovery of the Relevant NK Cell Subsets and Their Impact On HCT Outcomes
Rehan Mujeeb Faridi, PhD, University of Calgary; Taylor J Kemp, University of Calgary; Abdelhamid Liacini, PhD, University of Calgary; Poonam Dharmani, PhD, University of Calgary; Victor Lewis, MD, Alberta Children's General Hospital; Noureddine Berka, PhD, Calgary Laboratory Services; Jan Storek, MD, PhD, Tom Baker Cancer Centre/Foothills Hospital; Faisal Khan, PhD, University of Calgary

180
The Restorative Effect of Flt3-Ligand and IL-7 On CD4+ T Cell Homeostatic Proliferation During Graft-Versus-Host Disease
Simon-David Gauthier, University of Montreal; Martin Guimond, PhD, University of Montreal

181
NK Cell Recovery and Costimulatory Molecule Profiles After Autologous Hematopoietic Cell Transplantation (HCT) in Multiple Myeloma (MM) Patients
Myo Htut, MD, City of Hope; Ghislaine Gallez-hawkins, Beckman Research Institute, City of Hope National Medical Center; Joycelynne Palmer, PhD, City of Hope; Ricardo Spielberger, MD, City of Hope National Medical Center; Pablo M Parker, MD, City of Hope National Med Ctr; Len T Farol, MD, Kaiser Permanente/City of Hope; Anne Franck, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA; Laetitia Jeannet, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA; Eunicia Reburiano, Division of Biostatistics, City of Hope National Medical Center, Duarte, CA;; Valerie Jimenez, Division of Biostatistics, City of Hope National Medical Center, Duarte, CA;; Lupe Duarte, Division of Biostatistics, City of Hope National Medical Center, Duarte, CA; Andy Dagis, Division of Biostatistics, City of Hope National Medical Center, Duarte, CA; Firoozeh Sahebi, Kaiser Permanente Southern California, Duarte, CA; Chatchada Karanes, MD, City of Hope; Stephen J. Forman, MD, City of Hope National Medical Center; Amrita Y. Krishnan, MD, City of Hope Medical Center; John Zaia, Beckman Research Institute of City of Hope

182
Regulatory T Cells Are Resistant to Cyclophosphamide (Cy) Through Expression of Aldehyde Dehydrogenase (ALDH) Upon Allogeneic Stimulation
Christopher G. Kanakry, MD, The Johns Hopkins University; Sudipto Ganguly, PhD, The Johns Hopkins University; Christopher Thoburn, The Johns Hopkins University; Brandy Perkins, The Johns Hopkins University; Richard J. Jones, MD, The Johns Hopkins University; Allan D. Hess, PhD, The Johns Hopkins University; Leo Luznik, MD, The Johns Hopkins University

183
Laboratory Correlates of Immune Reconstitution At 1-Year Following Related, Unrelated, and Umbilical Cord Blood Hematopoietic Stem Cell Transplantation: Correlation with Survival
Takakazu Kawase, MD, PhD, Fred Hutchinson Cancer Research Center; Paul J Martin, MD, Fred Hutchinson Cancer Research Center; Mary E.D. Flowers, MD, Fred Hutchinson Cancer Research Center; Carina Moravec, ARNP, Fred Hutchinson Cancer Research Center; Barry Storer, PhD, Fred Hutchinson Cancer Research Center; John A. Hansen, MD, Fred Hutchinson Cancer Research Center; Edus H. Warren, MD, PhD, Fred Hutchinson Cancer Research Center

184
Pediatric Post Transplant Neutrophil Function
Michael W. Kent, MD, Bonfils Blood Center; Marguerite R. Kelher, MS, University of Colorado Denver; Christopher C. Silliman, MD, PhD, University of Colorado Denver

185
B Cell Engraftment in SCID Patients After Stem Cell Transplantation
Caridad Martinez, MD, Baylor College of Medicine, Texas Children's Hospital; William Shearer, MD, PhD, Baylor College of Medicine, Texas Children's Hospital; Sarah K Nicholas, MD, Baylor College of Medicine, Texas Children's Hospital; Jordan Orange, MD, PhD, Baylor College of Medicine, Texas Children's Hospital; Javier Chinen, MD, Baylor College of Medicine, Texas Children's Hospital; Howard Rosenblatt, MD, Dell Children's Medical Center and SFC; Jesse Wu, PhD, Baylor College of Medicine, Texas Children's Hospital; Catherine M. Bollard, MD, Baylor College of Medicine, Texas Children's Hospital; Kathryn Leung, MD, Baylor College of Medicine, Texas Children's Hospital; Malcolm K. Brenner, MD, PhD, Baylor College of Medicine, Texas Children's Hospital; Helen E Heslop, MD, Baylor College of Medicine, Texas Children's Hospital; Imelda C Hanson, MD, Baylor College of Medicine, Texas Children's Hospital; Robert A. Krance, MD, Baylor College of Medicine, Texas Children's Hospital

186
Assessment of the Effect of Nilotinib (Tasigna) Maintenance Therapy After Allogeneic Stem Cell Transplantation in Patients with Advanced CML and Ph+ ALL On Immune Reconstitution and Lymphocyte Function
Nira Varda-Bloom, Chaim Sheba Medical Center; Raz Somech, Chaim Sheba Medical Center; Yulia Volchek, MD, Chaim Sheba Medical Center; Jacqueline Davidson, Chaim Sheba Medical Center; Atar Lev, Chaim Sheba Medical Center; Ronit Yerushalmi, MD, Chaim Sheba Medical Center; Avichai Shimoni, MD, Chaim Sheba Medical Center; Arnon Nagler, MD, Chaim Sheba Medical Center

187
Evolution of T Cell Repertoire Diversity After Reduced-Intensity Conditioning and Double Umbilical Cord Blood Transplantation with or without Exposure to FT1050 (16,16-dimethyl Prostaglandin E2)
Sarah Nikiforow, MD PhD, Dana-Farber Cancer Institute; Sean M McDonough, MS, Dana-Farber Cancer Institute; Ryan O. Emerson, PhD, Adaptive Biotechnologies; David Hamm, MSc, Adaptive Biotechnologies; Haesook Kim, PhD, Dana-Farber Cancer Institute; Karen Ballen, MD, Massachusetts General Hospital; Vassiliki A Boussiotis, MD PhD, Beth Israel Deaconess Medical Center; Robert J. Soiffer, MD, Dana-Farber Cancer Institute; Joseph H Antin, MD, Dana-Farber Cancer Institute; Jerome Ritz, MD, Dana-Farber Cancer Institute; Corey Cutler, MD MPH FRCP(C), Dana-Farber Cancer Institute

188
Monitoring CMV-Specific CD8+ T-Cell Responses After Allogeneic Stem Cell Transplantation: A New Way of Guiding Anti-Viral Therapy
Amaya Zabalza, MD, Biomedical Research Center of Navarra; Miriam Ciaurriz, BsC, Biomedical Research Center of Navarra; Lorea Beloki, BsC, Biomedical Research Center of Navarra; Natalia Ramirez, BsC, PhD, Biomedical Research Center of Navarra; Ana Gorosquieta, MD, Complejo Hospitalario de Navarra; Mercedes Rodriguez Calvillo, MD, PhD, Complejo Hospitalario de Navarra; Eva Bandres, BsC, PhD, Complejo Hospitalario de Navarra; Cristina Mansilla, BsC, PhD, Biomedical Research Center of Navarra; Eduardo Olavarria, MD, PhD, Complejo Hospitalario de Navarra

189
Elevated Gamma Delta T Cell Recovery Following Hematopoietic Stem Cell Transplantation Associated with Improved Long Term Overall Survival in Pediatric Patients with Acute Leukemia
Ross Perko, MD, St. Jude Children's Research Hospital; Paul Thomas, PhD, St. Jude Children's Research Hospital; Guolian Kang, PhD, St. Jude Children's Research Hospital; Mari Hashitate Dallas, MD, St. Jude Children's Research Hospital

190
Vaccine Responses Following Unrelated Double Cord Blood Transplantation (CBT)
Trudy Small, MD, Memorial Sloan-Kettering Cancer Center; Marissa Lubin, BA, Memorial Sloan-Kettering Cancer Center; Andromachi Scaradavou, Memorial Sloan-Kettering Cancer Center; Christine Iovino, FNP-BC, Memorial Sloan-Kettering Cancer Center; Melanie Bushnell, ANP-BC, Memorial Sloan-Kettering Cancer Center; Juliet N. Barker, MBBS, (Hons), FRACP, Memorial Sloan-Kettering Cancer Center

191
Isolation, Expansion & Function of Cord Blood Natural Killer Cells
Suzanne L Tomchuck, PhD, St. Jude Children's Research Hospital; Wing Leung, MD, PhD, St. Jude Children's Research Hospital; Mari Hashitate Dallas, MD, St. Jude Children's Research Hospital

192
In Vivo Generation of Thymus-Independent T Cells in a Tissue-Engineered T Cell Development Supporting Microenvironment
Andrea Z. Tuckett, PhD, Memorial Sloan-Kettering Cancer Center; Xiaochuan Yang, PhD, Stevens Institute of Technology; Lichen Wang, Stevens Institute of Technology; Hongjun Wang, PhD, Stevens Institute of Technology; Marcel R. M. van den Brink, MD, PhD, Memorial Sloan-Kettering Cancer Center; Johannes L. Zakrzewski, MD, Memorial Sloan-Kettering Cancer Center

193
T Cell Immunotherapy Enabled by Imaging-Guided Injections of Lymphoid Organs
Andrea Z. Tuckett, PhD, Memorial Sloan-Kettering Cancer Center; Raymond H. Thornton, MD, Memorial Sloan-Kettering Cancer Center; Yusuke Shono, MD, PhD, Memorial Sloan-Kettering Cancer Center; Marcel R. M. van den Brink, MD, PhD, Memorial Sloan-Kettering Cancer Center; Johannes L. Zakrzewski, MD, Memorial Sloan-Kettering Cancer Center

194
Assessment of T-Cell Reconstitution After Two Step Haploidentical Stem Cell Transplants by Measurement of T-Cell Receptor Excision Circles (TREC)
John L. Wagner, MD, Kimmel Cancer Center, Thomas Jefferson University; Irina Kakhniashvili, MD, Kimmel Cancer Center Thomas Jefferson University; Bijoyesh Mookerjee, MD, Thomas Jefferson Medical College; Joanne Filicko, MD, Thomas Jefferson University Hospital; Dolores Grosso, DNP, Kimmel Cancer Center, Thomas Jefferson University; Neal Flomenberg, MD, Kimmel Cancer Center, Thomas Jefferson University

195
The Effect of Sirolimus Based Regimen On Immune Reconstitution After Allogeneic Stem Cell Transplantation
Jong-Ho Won, MD, PhD, Soon Chun Hyang University Hospital; Seong Kyu Park Sr., Soonchunhyang University Hospital; Se Hyung Kim Jr., Soonchunhyang Universit Hospital; Jina Yun Jr., Soonchunhyang Universit Hospital

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