Method: 383 patients underwent allogeneic HSCT (57% male; 82% White; mean age 50 y; 66% leukemia, 21% lymphoma). Pre-transplant, a social worker documented patients’ financial resources and educational background. Via census data, we derived median household income and high-school graduation rates at the census-block level. HSCT outcomes over six years were obtained from medical records.
Results: Controlling for demographics (age, gender, race, marital status) and medical factors (disease, pre-transplant chemotherapy, remission status, cell dose, donor-recipient CMV status, donor sex), greater pre-transplant financial resources were associated with longer survival (HR 1.55; p=0.007), as was higher median neighborhood income (HR 1.52; p=0.02). When entered simultaneously, higher financial resources (HR 1.45; p=0.03) and neighborhood income (HR 1.54, p=0.06) continued to predict longer survival. Adding educational attainment did not change the magnitude of these associations (financial resources HR 1.60; neighborhood income HR 1.90). Also, greater pre-transplant financial resources were associated with lower non-relapse mortality (NRM) than lower resources (HR 0.45; p=0.03).
Conclusions: Greater financial resources are associated with lower non-relapse mortality and higher 2-year overall survival post-HSCT. This association is independent of educational attainment, suggesting that it reflects the influence of resources as opposed to knowledge or health literacy.
See more of: Poster Abstracts