S-OA-E Oral Abstracts - Session E - GVH/GVL

Track: BMT Tandem "Scientific" Meeting
Thursday, February 12, 2015: 4:45 PM-6:45 PM
Seaport Ballroom DE (Manchester Grand Hyatt)
Chairs:
John Koreth, MBBS, DPhil and Pavan Reddy, MD

Disclosures:
J. Koreth, Nothing To Disclose

P. Reddy, Nothing To Disclose

35
Incidence, Risk Factors, and Prognosis of Late Immune-Mediated Disorders after Allogeneic Hematopoietic Cell Transplantation (HCT)
Mukta Arora, MD, MS, University of Minnesota Medical Center; Corey S. Cutler, MD, Dana-Farber Cancer Institute, Harvard Medical School; Madan H. Jagasia, MD, MBBS, MS, Vanderbilt University Medical Center; Joseph Pidala, MD, PhD, H. Lee Moffitt Cancer Center and Research Institute; Xiaoyu Chai, MS, Fred Hutchinson Cancer Research Center; Paul J. Martin, MD, Fred Hutchinson Cancer Research Center; Mary E. D. Flowers, MD, Fred Hutchinson Cancer Research Center; Yoshihiro Inamoto, MD PhD, National Cancer Center Hospital; George L Chen, MD, Roswell Park Cancer Institute; Bill Wood, University of North Carolina at Chapel Hill; Nandita Khera, MD, Mayo Clinic; Jeanne Palmer, MD, Mayo Clinic Arizona; Hien K. Duong, MD, Cleveland Clinic; Sally Arai, MD, Stanford University Medical Center; Stephanie J. Lee, MD, MPH, Fred Hutchinson Cancer Research Center

36
Respiratory Virus (RV) from Broncho Alveolar Lavage (BAL) Prior to Hematopoietic Cell Transplantation (HCT): A Strong Predictor for Allo-Immune Mediated Lung Syndromes (allo-LS)
Birgitta Versluys, MD, University Medical Center Utrecht; Marc Bierings, MD, PhD, University Medical Center Utrecht; Caroline A. Lindemans, MD, PhD, University Medical Center Utrecht; Kors Ent vd, Md, PhD, Wilhelmina Kinderziekenhuis, University Medical Center Utrecht; Tom Wolfs, MD, PhD, Wilhelmina Kinderziekenhuis, University Medical Center Utrecht; Jean Luc Murk, MD, PhD, University Medical Center Utrecht; Jaap-Jan Boelens, MD, PhD, University Medical Center Utrecht

37
Prevention of Acute Gvhd By Ex Vivo Expanded Umbilical Cord Blood Derived Regulatory T Cells (Treg)
Claudio G. Brunstein, MD, PhD, University of Minnesota Medical Center; Keli Hippen, University of Minnesota; Todd E Defor, MS, University of Minnesota; David McKenna, MD, University of Minnesota; Julie Curtsinger, University of Minnesota; Darin Sumstad, University of Minnesota Medical Center, Fairview; Bruce L Levine, PhD, University of Pennsylvania; Carl H. June, MD, University of Pennsylvania; Jeffrey S. Miller, MD, University of Minnesota; Michael R. Verneris, MD, University of Minnesota Medical Center, Fairview; Bruce R. Blazar, MD, University of Minnesota; John E. Wagner, MD, University of Minnesota

38
Defining the Primate T Cell Transcriptome during Gvhd: New Data Implicating Sonic Hedgehog and Aurora Kinase Pathways in Gvhd Pathogenesis and Prevention
Scott N Furlan, MD, Seattle Children's Research Institute; Benjamin K. Watkins, MD, Emory University; Angela Mortari, University of Minnesota; Bruce R. Blazar, MD, University of Minnesota; Cynthia Giver, Emory University; Edmund K. Waller, MD, PhD, Emory University; Leslie S. Kean, MD, PhD, Fred Hutchinson Cancer Research Center

39
Prognostic Impact of Follistatin in Acute Graft-Versus-Host Disease: Results from BMT CTN 0302 and 0802
Shernan Holtan, MD, University of Minnesota; Michael R. Verneris, MD, University of Minnesota; Kirk R. Schultz, MD, BC Childrens Hospital; Laura F Newell, MD, Oregon Health & Science University; Gabrielle Meyers, MD, Oregon Health & Science University; Fiona He, MD, University of Minnesota; Todd E Defor, MS, University of Minnesota; Margaret L. MacMillan, MD, MSc, FRCPC, University of Minnesota; Sarah Cooley, MD, University of Minnesota; Bruce R. Blazar, MD, University of Minnesota; Angela Panoskaltsis-Mortari, PhD, University of Minnesota; Daniel J. Weisdorf, MD, University of Minnesota Medical Center

40
Identification of CD137+ IFN-g- CD4+ Alloreactive T Cells Post Myeloablative Double Cord Blood Transplant: A Synergistic Role in the Graft Verus Graft Interaction
Jianqiang Li, PhD, MSc, MB, Fred Hutchinson Cancer Research Center; Joseph Blake, Fred Hutchinson Cancer Research Center; Colleen Delaney, MD, MSc, Fred Hutchinson Cancer Research Center

41
IL-22 Directly Regulates Intestinal Stem Cells, Protecting Epithelium from GvHD and Reducing GvHD Mortality
Caroline A. Lindemans, MD, PhD, University Medical Center Utrecht; Anna Mertelsmann, Memorial Sloan Kettering Cancer Center; Margaret O'Connor, Memorial Sloan Kettering Cancer Center; Marco Calafiore, Memorial Sloan Kettering Cancer Center; Jarrod A Dudakov, Memorial Sloan Kettering Cancer Center; Robert Jenq, MD, Memorial Sloan Kettering Cancer Center; Enrico Velardi, Memorial Sloan Kettering Cancer Center; Lauren Young, Memorial Sloan Kettering Cancer Center; Odette M. Smith, BA, Memorial Sloan Kettering Cancer Center; Gillian Lawrence, Memorial Sloan Kettering Cancer Center; Natalie Luo, Memorial Sloan Kettering Cancer Center; Juliet Ivanov, Memorial Sloan Kettering Cancer Center; Guoqiang Hua, Memorial Sloan Kettering Cancer Center; Laura Martin, Memorial Sloan Kettering Cancer Center; Chen Liu, University of Florida College of Medicine; Richard Kolesnick, Memorial Sloan Kettering Cancer Center; Marcel R. M. van den Brink, MD, PhD, Memorial Sloan Kettering Cancer Center; Alan M. Hanash, MD, PhD, Memorial Sloan Kettering Cancer Center

42
Physician-Reported CR+PR at 6 Months Predicts Subsequent Survival in Patients with Chronic Gvhd
Jeanne Palmer, MD, Mayo Clinic; Xiaoyu Chai, MS, Fred Hutchinson Cancer Research Center; Paul J. Martin, MD, Fred Hutchinson Cancer Research Center; Joseph Pidala, MD, PhD, H. Lee Moffitt Cancer Center and Research Institute; Aleksandr Lazaryan, MD MPH PhD, University of Minnesota Medical Center; Mukta Arora, MD, MS, University of Minnesota Medical Center; Corey S. Cutler, MD, Dana-Farber Cancer Institute, Harvard Medical School; Steven Z. Pavletic, MD, National Cancer Institute, National Institutes of Health; Iskra Pusic, MD, Washington University Medical Center; Madan H. Jagasia, MD, MBBS, MS, Vanderbilt University Medical Center; Yoshihiro Inamoto, MD PhD, National Cancer Center Hospital; Mary E. D. Flowers, MD, Fred Hutchinson Cancer Research Center; Georgia Vogelsang, MD, MBA, Johns Hopkins Medical Center; Stephanie J. Lee, MD, MPH, Fred Hutchinson Cancer Research Center